Water resources are inextricably linked to local livelihoods and wellbeing, agricultural production and food security, and local, national and the regional economies across the Mekong region. The Mekong, Red and Salween Rivers are all transboundary rivers that are subject to the dynamics of rapid change as the region increasingly integrates economically and socially. Whether development is inclusive, informed and accountable, and the rights and entitlements of marginalized communities recognized, remains a key challenge.